It sounds a little funny, but we're experts at drilling holes. We have powerful hydraulic paper drilling machines that feature many different sizes of paper drills and enable us to position the hole just about anywhere on the sheet of paper. Just remember to allow 1/2 an inch of extra margin for three-hole drilling along the side of the sheet of paper.
Here's an interesting note: Did you know studies have shown that people tend to save printed items longer if they are three-hole drilled? Marketing experts think that subconsciously we tend to feel like we need to put a three-hole drilled sheet into a ring binder or save it for future reference.